Peptide | Amino acid sequence | Anticancer Activity | Cancer Cell |
D-peptide A D-peptide B D-peptide C D-peptide D | RLYLRIGRR RLRLRIGRR ALYLAIRRR RLLLRIGRR | Cell membrane disruption | Human cervix, glioma, lung, mouse myeloma, African green monkey kidney |
D-K6L9 | LKLLKKLLKK LLKLL | Necrosis via membrane depolarization | Human prostate |
NRC-03 | GRRKRKWLRR IGKGVKIIGG AALDHL | Cell membrane lysis | Human breast |
NRC-07 | RWGKWFKKAT HVGKHVGKAA LTAYL | Cell membrane lysis | Human breast |
Gomesin | ZCRRLCYKQR CVTYCRGR | Unclear | Murine melanoma, human breast, colon and cervix adenocarcinoma |
Hepcidin TH2-3 | QSHLSLCRWC CNCCRSNKGC | Cell membrane lysis | Human cervix, hepatocellular carcinoma, fibrosarcoma |
Dermaseptin B2 | GLWSKIKEVG KEAAKAAAK AAGKAALGAV SEAV | Necrosis | Human prostate and breast |
PTP7 | FLGALFKALS KLL | Apoptosis induction | Human lung, breast and hepatocellular carcinoma |
MGA2 | GIGKFLHSAK KFGKAFVGEI MNSGGKKWKM RRNQF–WVKVQRG | Necrosis and apoptosis | Cervix and lung, melanoma, rat glioma |
HNP-1 | ACYCRIPACI AGERRYGTCI YQGRLWAFCC | Mediation of antitumor immunity | Mouse colon and brest |
Tachyplesin | KWCFRVCYRG ICYRRCR | Activation of the classic complement pathway | Human prostate |
Temporin-1CEa | FVDLKKIANI INSIF | Membrane disruption, calcium release, ROS production | Human breast |
NK-2 | KILRGVCKKI MRTFLRRISK DILTGKK | Necrotic death after peptide intercalation into phospholipid phosphatidylserine -containing membranes. | Human chronic myelogenous leukemia, histiocytic lymphoma, acute T cell leukemia, acute lymphoblastic leukemia, neuroblastoma, colorectal adenocarcinoma |
Bovine lactoferricin B6 (LbcinB6) | RRWQWR | Apoptosis, disruption of mitochondrial membrane | Human acute lymphoblastic T leukemia, acute T cell leukemia |
Cecropin CB1 | KWKVFKKIEK MGRNIRNGIV KAGPKWKVFK KIEK | Unclear | Human acute lymphoblastic T leukemia, lung carcinoma, stomach carcinoma |