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Spacer 18 also known as HEG spacer (hexaethylene glycol) is a 18 atom spacer can be placed at 5', 3' or internally.  These hydrophiolic PEG spacer can be inersted in the multiple additions when a longer spacer is required especially when coupling an enzyme or antibody to an oligonucleotide, where there is a need to add a hydrophilip spcaer such as this to optimize the coupling reaction. In addition, HEG spacer also act as a blocker to stop polymerase activity at the 3' terminus.

Contact Bio-Synthesis for Spacer 18, HEG Spacer Modified Oligonucleotide Synthesis Services.

Product Information

 

Product Name:

Spacer 18 (Hexaethylene glycol) Oligonucleotide Modification

Alternate Name:

PEG Spacer, HEG

Category:

spacer

Modification Code:

[Sp18]

Chemical Formula:

C12H25O9P

Exact Mass:

344.12

Formula Weight:

344.30

m/z:

344.12 (100.0%), 345.13(13.60%), 346.13(2.7%)

Elemental Analysis:

C, 41.86; H, 7.32; O, 41.82; P, 9.00

Structure:

Bio-Synthesis Inc. Oligo Structure

Purification:

HPLC or PAGE

Delivery Format:

Lyophilized

Shipping Conditions:

Room Temperature

Storage Conditions:

-20°C To -70°C
Oligonucleotides are stable in solution at 4°C for up to 2 weeks. Properly reconstituted material stored at -20°C should be stable for at least 6 months. Dried DNA (when kept at -20°C) in a nuclease-free environment should be stable for years.