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Carboxy-dT can be used in place of a dT in an internal position of the oligo, or as the 5' terminal base. The carboxy-dT modifier allows direct coupling of an oligo to a molecule or surface with a primary amino by a standard peptide coupling or via the intermediate N-hydroxy-succinimide (NHS) ester. This modifier is added to the oligo on the machine at the time of synthesis.

Product Information

 

Product Name:

dT-Carboxy Oligonucleotide Modification

Category:

carboxy linker, Minor Bases

Modification Code:

[CarboxydT]

Chemical Formula:

C13H15N2O9P

Exact Mass:

374.05

Formula Weight:

374.24

m/z:

374.05 (100.0%), 375.05 (14.8%), 376.06 (2.8%)

Elemental Analysis:

C, 41.72; H, 4.04; N, 7.49; O, 38.48; P, 8.28

Structure:

Bio-Synthesis Inc. Oligo Structure

Purification:

HPLC or PAGE

Delivery Format:

Lyophilized

Shipping Conditions:

Room Temperature

Storage Conditions:

-20°C To -70°C
Oligonucleotides are stable in solution at 4°C for up to 2 weeks. Properly reconstituted material stored at -20°C should be stable for at least 6 months. Dried DNA (when kept at -20°C) in a nuclease-free environment should be stable for years.

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