Amino TEG Modified Oligonucleotide
Amino TEG oligonucleotide modifer, a hydrophilic triethylene glycol ethylamine derivative, is a chemical modification that allows the functionalizing of oligonucleotides at the 5'-terminal end. 5'-Amino-modifier oligonucleotides are valuable tools in molecular biology, enabling a wide range of experimental and therapeutic strategies.
Adding an amino group to the 5'-end enhances the oligonucleotide's functionality and allows its use in various applications.
Oligonucleotides modified with a 5'-amino group make the following possible:
- Conjugation: An amino group at the 5'-end allows attaching other molecules, such as fluorescent dyes, biotin, or peptides, enabling versatile labeling or functionalization.
- Increased Stability: Modifying the 5'-end can improve the stability of oligonucleotides against enzymatic degradation.
- Enhanced Binding: The amino modifier enables the addition of other functionalities that can influence hybridization properties and potentially improve binding affinity to target sequences.
- Bioactivity: Amino group-modified oligonucleotides allow the design to facilitate interactions with proteins or other biomolecules, making them useful in therapeutic or diagnostic applications.
Contact BioSynthesis for additional information regarding
Amino TEG Oligonucleotide Modification.
Product Information
Amino TEG Modified Oligonucleotide
-20°C To -70°C
Oligonucleotides are stable in solution at 4°C for up to 2 weeks. Properly reconstituted material stored at -20°C should be stable for at least 6 months. Dried DNA (when kept at -20°C) in a nuclease-free environment should be stable for years.
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