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3'-Deoxyadenosine, 3'dA also known as cordycepin, this sugar modified base which used to substitute 2'-5' phosphodiester linage for the usual 3'-5' linkage at some or all position of an oligonucleotide. Oligonucleotide containing primary 2'-5' linkage can selectlively bind to complementary sing-stranded 3'-5' RNA over comparable 3'-5' DNA 1,2 which could be useful in antisense application or as  ssRNA-specific probe2. Contact us for 2-5 linked oligonucleotide synthesis

 

Product Information

 

Product Name:

3'-Deoxyadenosine, Cordycepin,2'-5' Linked Oligonucleotide Modification

Alternate Name:

3'dA (2'-5' linked)

Category:

End blocker, Antisense, sugar modified bases

Modification Code:

[3'dA2-5]

Chemical Formula:

C10H12N5O5P

Exact Mass:

313.06

Formula Weight:

313.21

Structure:

Bio-Synthesis Inc. Oligo Structure

Purification:

HPLC or PAGE

Delivery Format:

Lyophilized

Shipping Conditions:

Room Temperature

Storage Conditions:

-20°C To -70°C
Oligonucleotides are stable in solution at 4°C for up to 2 weeks. Properly reconstituted material stored at -20°C should be stable for at least 6 months. Dried DNA (when kept at -20°C) in a nuclease-free environment should be stable for years.