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Biosynthesis, Inc. has launched a new peptide conformation screening tool called positional cyclization scanning. This technique involve synthesis of peptides with constrained structures in the form of lactam bridge or stapling at various position to determine the overall structure conformation of the protein. This process not only provides peptides with desirable pharmacokinetic properties but also provides a conceptual approach towards designing of peptidomimetics and small molecules for intracellular protein-protein interactions. |
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Advantages of constrained peptides: |
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Enhance receptor affinity and efficacy |
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Increased cell permeability |
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Decrease proteolysis hence increased bio-activities |
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Visit our booth 104 at: |
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ABRF 2011,
San Antonio Texas,
Feb 19-22
22nd APS Symposium
San Diego California,
June 25-30 |
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We are located at: |
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Biosynthesis, Inc.
800 Mario Court
Lewisville TX, 75057
USA
Phone: 972-420-8505
Toll Free: 1-800-227-0627
Fax: 972.420.0442
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Email: info@biosyn.com
www.biosyn.com |
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Bio-Synthesis is a leading global manufacturer of high quality custom-synthesized peptides. With over 20 years of experience, service and technical expertise we have provided peptides with high standards of quality to biomedical community, biotechnology and pharmaceutical companies. We continue to maintain integrity and professionalism as we serve our clients in areas spanning from proteomic to cell biology. |
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Custom Oligo Synthesis |
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Organic Synthesis |
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Detection and Analysis |
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Bioconjugation |
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Custom Polyclonal Antibody Services |
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