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WP9QY TNF - alpha Antagonist

WP9QY TNF - alpha Antagonist
Sequence (1LC):
YCWSQYLCY (Disulfide bridge: 2-8)
Sequence (3LC):
NH2 - Tyr - Cys - Trp - Ser - Gln - Tyr - Leu - Cys - Tyr - COOH (Disulfide bridge: 2 - 8)
Catalog :
13995-01
Unit:
1mg
Price/Unit:
$431  (For other quantities please Contact Us or call 972-420-8505 (USA) 800-227-0627 (INTL.) or Fax 972.420.0442)
Purity:
>95%
Format:
Each vial contains lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt
Description:
This cyclic peptide is designed to mimic the most critical tumor necrosis factor (TNF) recognition loop on TNF receptor I. It prevents interactions of TNF with its receptor. This TNF antagonist is a useful template for the development of small molecular inhibitors to prevent both inflammatory bone destruction and systemic bone loss in rheumatoid arthritis.
Storage:
Store the peptide at -20°C. Keep container tightly
Product Usage:
This product is for research use only. Not for use in diagnostic or therapeutic procedures.
M.W.:
1226.4g/mol
Reference/Citations:
Saito, H. et al. Arthritis Rheum. 56, 1164 (2007).