VIR - 165, Alpha1 - Antitrypsin Modification (353 - 372)
VIR - 165, Alpha1 - Antitrypsin Modification (353 - 372)
Sequence (1LC):
LEAIPCSIPPCFAFNKPFVF
Sequence (3LC):
H - Leu - Glu - Ala - Ile - Pro - Cys - Ser - Ile - Pro - Pro - Cys - Phe - Ala - Phe - Asn - Lys - Pro - Phe - Val - Phe - OH
Price/Unit:
$912
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Format:
Lyophilized solid, trifluoroacetate (TFA) salt format
Description:
This 20 residues virus inhibitory peptide (VIRIP) corresponding to the c-proximal region of alpha1-antitrypsin, the most abundant circulating serien protease inhibitor. This VIRIP inhibits a wide variety of HIV-1 strains and blocks HIV-1 entry by interacting with the gp41 fusion peptide.
Product Usage:
This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Reference/Citations:
- Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide. Münch, J. et al. Cell 129, 263 (2007).
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