Linear C5a Receptor Antagonist, mouse, human
Linear C5a Receptor Antagonist, mouse, human
Sequence (1LC):
FKP-(D-Cha)-Wr
Sequence (3LC):
NH2 - Phe - Lys - Pro - D - Cha - Trp - D - Arg - COOH
Price/Unit:
$405
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Format:
Each vial contains lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt
Description:
This linear peptide is derived from the C-terminus of the chemokine, complement fragment 5 anaphylatoxin (C5a). This peptide functions to inhibit C5a binding and function at human and rat C5a receptors. C5a is crucial to triggering cellular immune responses and its overexpression is involved in arthritis, Alzheimer’s disease, cystic fibrosis, systemic lupus erythematosus, and other immunoinflammatory diseases
Storage:
Store the peptide at -20°C. Keep container tightly
Product Usage:
This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Reference/Citations:
Higginbottom, A. J Biol Chem 280, 17831 (2005); Buck, E. et al. PNAS 102, 2719 (2005).
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