C5a Receptor Agonist, mouse, human
C5a Receptor Agonist, mouse, human
Sequence (1LC):
FKP-(D-Cha)-Cha-r
Sequence (3LC):
NH2 - Phe - Lys - Pro - D - Cha - Cha - D - Arg - COOH
Price/Unit:
$405
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Format:
Each vial contains lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt
Description:
This peptide is derived from the C-terminus of the chemokine, complement fragment 5 anaphylatoxin (C5a). This peptide functions as a C5a receptor agonist. C5a is a plasma protein involved in cellular inflammatory processes by inducing chemotaxis, degranulation of leukocytes, increased vascular permeability, and cytokine production. The cyclohexylalanine at position 5 is crucial to agonist function. Arg at the last position is of the d-isomer.
Storage:
Store the peptide at -20°C. Keep container tightly
Product Usage:
This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Reference/Citations:
Buck, E. et al. PNAS 102, 2719 (2005); Higginbottom, A. J Biol Chem 280, 17831 (2005).
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