800.227.0627
Beta-Amyloid (1-40) Binding Peptide, FAM-labeled
Sequence (1LC):
5-FAM-DWGKGGRWRLWPGASGKTEA
Sequence (3LC):
5-FAM - Asp - Trp - Gly - Lys - Gly - Gly - Arg - Trp - Arg - Leu - Trp - Pro - Gly - Ala - Ser - Gly - Lys - Thr - Glu - Ala - COOH
Catalog :
13758-01
Unit:
0.1 mg
Price/Unit:
$728  (For other quantities please Contact Us or call 972-420-8505 (USA) 800-227-0627 (INTL.) or Fax 972.420.0442)
Purity:
>95%
Format:
Each vial contains lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt
Description:
This 5-FAM-labeled (Ex/Em=494 nm/521 nm) 20 amino acid peptide binds to the polymer form of b-Amyloid (1-40) but not to monomeric beta-Amyloid (1-40). This sequence represents a new potential carrier molecule to deliver drugs to amyloid plaques in Alzheimer's disease (AD) patients and to image plaques in AD brains. The ability to directly target reagents to the amyloid form of the beta-Amyloid peptide may allow the delivery of neuroprotective agents to make amyloid plaques less toxic, the delivery of amyloid-destroying molecules to eliminate plaques, or the delivery of reagents to prevent amyloid plaque formation.
Storage:
Store the peptide at -20°C. Keep container tightly
Product Usage:
This product is for research use only. Not for use in diagnostic or therapeutic procedures.
M.W.:
2573.8 g/mol
Reference/Citations:
  1. Kang, C. et al. Neurobiol. Dis. 14, 146 (2003).