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[Ala16,17,20]-β-Amyloid (1-28)

[Ala16,17,20]-β-Amyloid (1-28)
Sequence (1LC):
DAEFRHDSGYEVHHQAAVFAAEDVGSNK
Sequence (3LC):
NH2 - Asp - Ala - Glu - Phe - Arg - His - Asp - Ser - Gly - Tyr - Glu - Val - His - His - Gln - Ala - Ala - Val - Phe - Ala - Ala - Glu - Asp - Val - Gly - Ser - Asn - Lys - COOH
Catalog :
13721-01
Unit:
1 mg
Price/Unit:
$1,098  (For other quantities please Contact Us or call 972-420-8505 (USA) 800-227-0627 (INTL.) or Fax 972.420.0442)
Purity:
>95%
Format:
Each vial contains lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt
Description:
This is a mutated β-Amyloid 1 to 28 amino acids sequence in which the KLVFF sequence (Ab16-20) is substituted with AAVFA. The KLVFF is the shortest peptide displaying consistent high binding capacity to full-length Aβ. The first, second, and fifth residues (i.e. KLXXF) are critical for binding. The substitutions in this Aβ (1-28) amino acids sequence in the 16 to 20 region profoundly impair the ability of the peptide to aggregate and form amyloid-like fibrils.
Storage:
Store the peptide at -20°C. Keep container tightly
Product Usage:
This product is for research use only. Not for use in diagnostic or therapeutic procedures.
M.W.:
3087.2 g/mol
Reference/Citations:
  1. Tjernberg, L. et al. J. Biol. Chem. 271, 8545 (1996).