Version History for Oligo Designer

Oligo Designer » Oligo Designer Accepted Inputs and Definition

Version Release Date Description

1.0

02/25/11
  • New: Oligo Designer which can calculate the following:
    • New: DNA nmoles
    • New: DNA nmole/OD260
    • New: DNA µg
    • New: DNA µg/OD260
    • New: DNA Anhydrous MW
    • New: DNA Basic Tm Calculation
    • New: DNA Salt Adjusted Tm Calculation
    • New: DNA GC Content
    • New: DNA Extinction Coefficient
    • New: Valid Sequence Length
    • New: DNA "Sequence:" field that removes non alphabet characters
    • New: DNA Reverse Complement

1.1

03/01/11
  • New: Dynamic "Computed Sequence" row shows removed characters due to invalid entries
  • New: Google Analytic script added
  • New: All sequence displays in groups of threes after computation
  • Fixed: Extinction coefficient bug that can cause page to crash
  • Fixed: Layout alignment issues
  • Updated: DNA "Sequence:" field removes all non-computable inputs
  • Updated: Defaults to 10 OD instead of having user input OD every time

1.2

03/29/11
  • Improved: Refined layout so that sequence can better fit table structure
  • Improved: Refined text formating of assumptions
  • New: Oligo Designer which can calculate the following:
    • New: RNA nmoles
    • New: RNA nmole/OD260
    • New: RNA µg
    • New: RNA µg/OD260
    • New: RNA Anhydrous MW
    • New: RNA Basic Tm Calculation
    • New: RNA Salt Adjusted Tm Calculation for sequence greater than 20
    • New: RNA GC Content
    • New: RNA Extinction Coefficient
    • New: RNA "Sequence:" field removes all non-computable inputs
    • New: RNA Reverse Complement
  • New: Added "Version History" documentation
  • New: Added "Accepted Input" documentation

1.3

04/21/11
  • New: Added Protein Translation feature that can output protein sequence code based on DNA or RNA sequence that do not have mixed bases
  • New: Toggle button to display protein sequence in 1 or 3 letter code
  • New: Toggle button to display DNA and RNA complements begining from 5' or 3'
  • New: Shows N/A for applicable output fields if completely invalid sequence has been entered
  • New: Added a shortcut icon to all pages of Oligo Designer
  • New: Added Breadcrumb to Oligo Designer Accepted Inputs and Definition page and Version History for Oligo Designer page
  • New: Limited sequence input to 250 bases
  • Fixed: Minor DNA sequence misalignment

1.4

05/27/11
  • New: Can output all possible combinations of DNA and RNA sequence that contains mixed bases
  • New: Protein Translation feature can now output all possible combinations of protein sequence code based on DNA or RNA sequence that has mixed bases
  • Fixed: Alternating row styling issues associated with some older browsers
  • Improved: Image button rollover responsiveness
  • Updated: Rewrote large portions of the code to make it more organized and scalable
  • New: Cannot enter more than 11 Mixed Bases since it can cause performance issues ('R' 'Y' 'K' 'M' 'S' 'W' 'B' 'D' 'H' 'V' 'N')

1.41

07/27/11
  • Fixed: "N/A" will now show at the Protein Results row when the inputed sequence is too short to map to any Amino Acids

1.42

08/16/11
  • Updated: Increased sequence input limit to 350 bases after many requests

1.5

08/23/11
  • New: Ability to input µg instead of OD as calculation parameter

1.51

08/24/11
  • Fixed: An error where computed combinations of mixed bases in RNA mode do not have their T replaced with U

1.52

02/13/12
  • Fixed: An error where length validator counted spaces as part of the length thus restricting maximun stated length to be entered when spaces are included
  • Updated: Increased sequence input limit to 450 bases after many requests