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15 + 5 Double Coupon Special   Molecular weight marker Budget saving special   Bio-Synthesis Unveils Free Online Software ‘Peptide, Oligo, Protein Analysis’ Click on Gizmo   All Highlights   All Events     Enter Keyword         Advance Search                       View Our Blog                 Custom siRNA Synthesis - Modifications RNAi - miRNA Synthesis and Purifications Modifications Design Quality Control Antisense oligonucleotides The siRNA can be modified with various base modifications like 2'O methyl RNA, LNA, biotin or digoxigenin. Based on the researchers need. All these modifications available from BioSynthesis are based on 0.2 umole synthesis scale and extensively purified using the most appropriate purification methods. Other scales, overhang chemistry and base contents are available upon request. Duplex siRNA - 21-mer Our siRNA oligos are available at a fixed price per oligonucleotide which are made of 19 RNA bases plus 2 DNA bases 3' overhang. Contact us for longer oligos or spike oligos. Modifications Synthesis scale, $/base 200 nmol 1 umol 10 umol phosphorothioates (S-oligo)* $4.25 $6.50 Inquire Biotin dT $220.00 $310.00 Inquire 5' or 3' biotinyalation $90.00 $190.00 Inquire 3' - Biotin TEG $275.00 $275.00 Inquire 5' or 3' phosphorylation $55.00 $110.00 Inquire 5' or 3' acridine $90.00 $190.00 Inquire 5' or 3' fluorescein $90.00 $190.00 Inquire 5' or 3' amino linker (C3, C6 or C12) $85.00 $150.00 Inquire Minor bases deoxyinosine(dI), deoxyuridine (dU) $25.00 $55.00 Inquire Minor bases 5 bromodeoxycytosine (5-Br-dC), 5 methyl dC, 5 iodo dC, 5 iodo dU, 5 fluoro dU $75.00 $125.00 Inquire digoxigenin $275.00 $350.00 Inquire Alkaline Phosphatase# $550.00 $1200.00 Inquire TET, HEX, 6-FAM $150.00 $200.00 Inquire         *Minimum charge for 15-mer applies. Labelings Synthesis scale, $/base Position 200 nmol (3 OD) 1.0 umole (5 OD) 3' -Alexa Fluor 488 Sense Strand $275.00 $275.00 3' -Alexa Fluor 546 Sense Strand $275.00 $275.00 3' -Alexa Fluor 555 Sense Strand $275.00 $275.00 3' -Alexa Fluor 647 Sense Strand $275.00 $275.00 3' - Cy3 Sense Strand $385.00 $385.00 3' - Cy5 Sense Strand $385.00 $385.00 3' - Dabcyl Sense Strand $275.00 $275.00 3' - Flurosecein, 6 - FAM, TET, Hex Sense Strand $275.00 $275.00 3' - Rhodamine, TAMRA Sense Strand $325.00 $325.00         *Minimum charge for 15-mer applies. Other modifications of custom siRNA may be available. Please contact us.   The most trusted name in Quality Custom Synthesis

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