To provide you with quality peptide product for the results you can trust...
Custom Long Peptide Synthesis
BIO-SYNTHESIS provides custom peptides and has developed a proprietary synthesis strategy that allows the synthesis of peptides that are quiet long in length - up to about 120 residues - with purity and speed, generally only possible with shorter peptide fragments.
Since most biologically active proteins are about 150 residues in length, however, it has been shown that most activity is kept within 100 residues. Most commercial proteins are made by recombinant methods, whereby genes coding for particular peptide sequences are inserted into a host organism, for bulk synthesis. While the endotoxin contamination can be problematic for recombinant methods, chemical synthesis offers much cleaner products.
BSI has decades of experience in synthesizing >500,000 custom peptides, many of them long peptides. This growing demands of using peptide or peptide like compounds for pharmaceutical drug discoveries. However, the challenge of long peptide synthesis is to overcome the enormous cumulative effect of yield. This is prohibited by synthetic inefficiencies associated with peptide aggregation such as slow or incomplete coupling and/or deprotection reactions
Bio-Synthesis has developed a solid-phase synthesis technology that overcomes these limitations, achieving syntheses of large proteins entirely by chemical methods. Our team of experts will examine your protein of interest and will assess feasibility to maximize success for synthesis of long and difficult peptides.
For quotation on long peptide synthesis, click here!
Service Features:
MALDI-TOF mass spectrometry for identification and characterization
HPLC for purity
Amino Acid Analysis
Peptide sequencing is also available upon requests.
Please call 800-227-0627 or write to us at biosyn@biosyn.com for details
For short (<5 residues) peptide molecule synthesis, click here!
