Version History: Peptide Design Library
Contents:
1. PL 3.0 (Latest)
2. PL 2.2 (Beta)
3. PL 1.0 (Beta)
- New: HTML documentation of all the formulae and constant input values used in the tool
- New: Version history of the tool
- Improved: Minimum sequence length required for isoelectric point calculation was modified from 10 residues to any length
- Improved: The old blurry images were replaced with better pixel images for improving clarity
- Fixed: The disappearance of the input sequence when the user traverses to another library of the application was fixed
- Fixed: The inability to export results to excel for overlapping library was fixed
- New: T-cell truncated library was added to the tool
- New: 3-positional and multi positional library options were added to Positional library
- New: Combinatorial 3-positional scan and multi positional library option were added to Random library
- New: Formulae to calculate isoelectric point, chemical formula, net charge, charge at pH 7 and amino acid composition for the output peptide sequences were added
- New: Database search option to fetch the input sequence from protein databases using accession numbers was added
- New: File upload option to input sequence from either a text file or a word document
- 6 various libraries were developed to generate peptide libraries
- Overlapping library
- Alanine scanning library
- Truncation library
- Positional scanning library
- Random library
- Scrambled library
- Input options to enter the sequence by copy (Ctrl+C) and paste (Ctrl+V) method was provided
- The maximum length of the input sequence was set to 1000 residues
- Show Colors option was provided to represent hydrophobic classification of residues in Overlapping Library, Truncated Library and Scrambled Library
- Stair Step option to represent the amino acid residue overlap in Overlapping Library was provided
- Formulae to calculate molecular weight and ratio of hydrophilicity for the output peptide sequences were added
- Option to export the results to MS excel, MS word and Notepad was provided
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