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Custom
DNA Synthesis-- FASTEST services in the industry |
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The use of antisense oligonucleotides (ASO’s) was first
described over twenty years ago as a method to arrest
gene expression levels both in vitro and in
vivo where single-stranded DNA or RNA, in antisense
configuration to a target sense mRNA. The strategies in
the design and chemistry of antisense compounds have
become an effective tool in molecular biology basic
research, genomics, proteomics, target screening/validation
and drug discovery.
BSI currently offer antisense oligos synthesized using DNA, 2'-O-Methyl RNA, RNA, or LNA bases with either phosphorothioate or unmodified
internucleotide bonds.
| Features |
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No set up fee |
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Deprotected, desalted, lyophilized |
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Purification by PAGE or RP-HPLC upon request |
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QC analysis by MALDI-TOF Mass spec, HPLC or
PAGE |
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Fast delivery with high throughput capacity |
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| Product Pricing |
| Scale |
100 nmole |
200 nmole |
400 nmole |
1
µmole |
| DNA Base |
$0.5/base |
$0.90/base |
$1.50/base |
$2.00/base |
| Phosphorothioate Bond |
Synthesis +
$40 |
Synthesis +
$40 |
Synthesis
+ $50 |
Synthesis
+ $50 |
| RNA Base |
$7.00/base |
$9.00/base |
$15.00/base |
$18.00/base |
| 2'-OMe |
$9.00/base |
$11.00/base |
$16.00/base |
$19.00/base |
| LNA (Lock
Nucleic Acids) |
$25.00/base |
$30.00/base |
$40.00/base |
$45.00/base |
| 5-Methyl dC |
Synthesis +
$45 |
Synthesis +
$45 |
Synthesis +
$90 |
Synthesis +
$90 |
A minimum will applied for oligo <10 bases. Yields and base price may vary depending
on type of antisense synthesis.
Large
scale synthesis is available upon
requests.
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contact us at 800-227-0627 or write to us at biosyn@biosyn.com
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| Purifications |
| Product |
Yields |
RNase-Free HPLC |
PAGE |
| 100 nmole |
(1 OD) |
$65 |
N/A |
| 200 nmole |
(2 ODs) |
$65 |
$65 for DNA
base |
| $150 for RNA, 2'-OMe, LNA, 5-Methyl dC |
| 400
nmole |
(5 ODs) |
$100 |
Inquire |
| 1µmole |
(10 ODs) |
$150 |
Inquire |
| An additional
1-2 days of turnaround time is required for
purifications. |
| click
here for recommended purification and applications! |
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The most trusted
name in Quality Custom Synthesis |
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